RedactedNarrative: Vessel 1 was anchored out near Colbert county side on Pickwick lake. Vessel 2 had left an island referred to as Sandy beach. Vessel 1 advised they saw vessel 2 coming directly at them and began yelling and waving their hands. Vessel 2 advised they did not see any lights on Vessel 1. Vessel 2 ran into and ramped over vessel 1. There were 2 females on vessel 1 that needed medical attention. The vessels made it back to Florence harbor where they received medical attention. The two females were transported to ECM hospital for cuts and bruising. I was unable to test vessel 1 navigational lights due to damage to the helm.